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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00375


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00375
General rule information [?]

Accession PRU00375
Dates 13-DEC-2004 (Created)
21-NOV-2019 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS51034; ZP_2
Name ZP domain
Function The zona pellucida (ZP) domain is a protein polymerization module of ~260 amino acid module, which is found at the C-terminus of many secreted eukaryotic glycoproteins that play fundamental roles in development, hearing, immunity, and cancer.
Scope(s) Eukaryota
Metazoa
Example(s) P60852;

Propagated annotation [?]

Cross-references [?]

PROSITE PS00682; ZP_1; 1;

Features [?]

From: PS51034
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="ZP #"

Additional information [?]

Size range 245-280 amino acids
Related rules None
Fusion None
Repeats 1
Topology Not cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]