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annotation rule: PRU00375

General rule information [?]

Accession PRU00375
Dates 13-DEC-2004 (Created)
16-DEC-2016 (Last updated, Version 2)
Data class Domain
Predictors PROSITE; PS51034; ZP_2
Name ZP domain
Function The zona pellucida (ZP) domain is a protein polymerization module of ~260 amino acid module, which is found at the C-terminus of many secreted eukaryotic glycoproteins that play fundamental roles in development, hearing, immunity, and cancer.

Propagated annotation [?]


Cross-references [?]

PROSITE PS00682; ZP_1; 1;

Features [?]

From: PS51034
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       ZP #        

Additional information [?]

Size range 245-280 amino acids
Related rules None
Repeats 1
Topology Not cytoplasmic
Example P60852 (ZP1_HUMAN)
Scope
Eukaryota; Metazoa

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]