ProRule PRU00375
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU00375 |
| Accession | PRU00375 |
| Dates | 13-DEC-2004 (Created)
21-NOV-2019 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51034; ZP_2 |
Name | ZP domain |
| Function | The zona pellucida (ZP) domain is a protein polymerization module of ~260 amino acid module, which is found at the C-terminus of many secreted eukaryotic glycoproteins that play fundamental roles in development, hearing, immunity, and cancer. |
| Scope(s) |
Eukaryota Metazoa |
| Example(s) | P60852 (ZP1_HUMAN); |
Propagated annotation
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Cross-references
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| PROSITE | PS00682; ZP_1; 1; |
Features
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| From: PS51034 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="ZP #" | |||||||||
Additional information
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| Size range | 245-280 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Not cytoplasmic |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [88] All [ 88 ]
- Retrieve set of proteins with 3D structure for this domain