ProRule PRU00380
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU00380 |
| Accession | PRU00380 |
| Dates | 6-JAN-2005 (Created)
27-JUN-2022 (Last updated, Version 10) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51054; ORANGE |
Name | Orange domain |
| Function | The Orange domain is a ~35 residue domain of unknown function, present in eukaryotic DNA-binding transcription repressors which regulate cell differentiation, embryonic patterning and other biological processes in both vertebrates and invertebrates. |
| Scope(s) |
Eukaryota Metazoa |
| Example(s) | O14503 (BHE40_HUMAN); |
Propagated annotation
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Comments
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| SUBCELLULAR LOCATION | Nucleus. |
Keywords
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Gene Ontology
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| GO:0005634; Cellular component:nucleus |
| GO:0006355; Biological process:regulation of DNA-templated transcription |
| GO:0006351; Biological process:DNA-templated transcription |
Features
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| From: PS51054 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Orange #" | |||||||||
Additional information
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| Size range | 20-45 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Not cytoplasmic |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [68] All [ 68 ]
- Retrieve set of proteins with 3D structure for this domain