ProRule PRU00389
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU00389 |
| Accession | PRU00389 |
| Dates | 21-JAN-2005 (Created)
21-NOV-2019 (Last updated, Version 7) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51064; IRS_PTB |
Name | IRS-type PTB domain |
| Function | IRS-type PTB domain has an average length of about 100 amino acids. It binds to the insulin receptor through the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins. |
| Scope(s) |
Eukaryota |
| Example(s) | Q99704 (DOK1_HUMAN); P35568 (IRS1_HUMAN); |
Propagated annotation
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Cross-references
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| PROSITE | PS51064; IRS_PTB; 1; |
Features
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| From: PS51064 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="IRS-type PTB #" | |||||||||
Additional information
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| Size range | 105 amino acids |
| Related rules |
none |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [44] All [ 44 ]
- Retrieve set of proteins with 3D structure for this domain