ProRule PRU00398
General rule information
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| Accession | PRU00398 |
| Dates | 11-FEB-2005 (Created)
21-NOV-2019 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51060; PARP_ALPHA_HD |
Name | PARP alpha-helical domain |
| Function | The poly(ADP-ribose) polymerase (PARP) alpha-helical domain is thought to relay the activation signal issued on binding to damaged DNA. |
| Scope(s) |
Eukaryota |
| Example(s) | P09874 (PARP1_HUMAN); |
Propagated annotation
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Features
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| From: PS51060 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="PARP alpha-helical #" | |||||||||
Additional information
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| Size range | 115-140 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Not cytoplasmic |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [35] All [ 35 ]
- Retrieve set of proteins with 3D structure for this domain