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annotation rule: PRU00398

General rule information [?]

Accession PRU00398
Dates 11-FEB-2005 (Created)
21-NOV-2019 (Last updated, Version 3)
Data class Domain
Predictors PROSITE; PS51060; PARP_ALPHA_HD
Name PARP alpha-helical domain
Function The poly(ADP-ribose) polymerase (PARP) alpha-helical domain is thought to relay the activation signal issued on binding to damaged DNA.

Propagated annotation [?]

Features [?]

From: PS51060
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       PARP alpha-helical #        

Additional information [?]

Size range 115-140 amino acids
Related rules None
Repeats 1
Topology Not cytoplasmic
Example P09874 (PARP1_HUMAN)


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]