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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00398


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00398
General rule information [?]

Accession PRU00398
Dates 11-FEB-2005 (Created)
21-NOV-2019 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS51060; PARP_ALPHA_HD
Name PARP alpha-helical domain
Function The poly(ADP-ribose) polymerase (PARP) alpha-helical domain is thought to relay the activation signal issued on binding to damaged DNA.
Scope(s) Eukaryota
Example(s) P09874;

Propagated annotation [?]

Features [?]

From: PS51060
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="PARP alpha-helical #"

Additional information [?]

Size range 115-140 amino acids
Related rules None
Fusion None
Repeats 1
Topology Not cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]