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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00403


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00403
General rule information [?]

Accession PRU00403
Dates 15-FEB-2005 (Created)
21-NOV-2019 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS51070; SHD
Name Stonin homology domain (SHD)
Function The ~140 amino-acid SHD domain may be unique to members of the stonin family, which are supposed to be endocytotic proteins involved in clathrin-mediated endocytosis at synapses. Its function is not yet known.
Scope(s) Eukaryota
Metazoa
Example(s) Q24212;

Propagated annotation [?]

Keywords [?]

Endocytosis
Membrane
Synapse

Gene Ontology [?]

GO:0006897; Biological process:endocytosis
GO:0016020; Cellular component:membrane
GO:0045202; Cellular component:synapse

Features [?]

From: PS51070
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="SHD #"

Additional information [?]

Size range 130-180 amino acids
Related rules None
Fusion None
Repeats 1
Topology Cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]