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annotation rule: PRU00404

General rule information [?]

Accession PRU00404
Dates 15-FEB-2005 (Created)
16-DEC-2016 (Last updated, Version 5)
Data class Domain
Predictors PROSITE; PS51072; MHD
Name Mu homology domain (MHD)
Function The MHD domain is found in endocytotic proteins involved in clathrin-mediated endocytosis and has been shown to bind to the C2B domain of members of the synaptotagmin family.

Propagated annotation [?]

Gene Ontology [?]

GO:0006886; Biological process: intracellular protein transport.
GO:0030131; Cellular component: clathrin adaptor complex.

Keywords [?]

Features [?]

From: PS51072
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       MHD #        

Additional information [?]

Size range 240-345 amino acids
Related rules None
Repeats 1
Topology Cytoplasmic
Example P38153 (AP3M_YEAST)


PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.

UniProtKB rule member sequences [?]