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| annotation rule: PRU00404 |
General rule information
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| Accession | PRU00404 |
| Dates | 15-FEB-2005 (Created) 21-NOV-2019 (Last updated, Version 6) |
| Data class | Domain |
| Predictors | PROSITE; PS51072; MHD |
| Name | Mu homology domain (MHD) |
| Function | The MHD domain is found in endocytotic proteins involved in clathrin-mediated endocytosis and has been shown to bind to the C2B domain of members of the synaptotagmin family. |
Propagated annotation
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Gene Ontology
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GO:0006886; Biological process: intracellular protein transport.
GO:0030131; Cellular component: clathrin adaptor complex.
GO:0030131; Cellular component: clathrin adaptor complex.
Keywords
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Features
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| From: PS51072 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | MHD # | |||||||||
Additional information
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| Size range | 240-345 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Cytoplasmic |
| Example | P38153 (AP3M_YEAST) |
| Scope | Eukaryota |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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UniProtKB/Swiss-Prot sets
Eukaryota [94]
- Retrieve set of proteins with 3D structure for this domain