ProRule PRU00415
General rule information
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Accession | PRU00415 |
Dates | 7-APR-2005 (Created)
21-NOV-2019 (Last updated, Version 8) |
Data class | Domain; |
Predictors |
PROSITE; PS50015; SAP_B |
Name | Saposin B-type domain |
Function | The saposin B-type domain is a ~80 amino acid domain present in saposins and related proteins that interact with lipids. In plant aspartic proteinases the two subdomains that are connected by disulfide bridges occur in inversed order, these "swapped" halves are called a "swaposin" domain. |
Scope(s) |
Eukaryota |
Example(s) | P07602 (SAP_HUMAN); |
Propagated annotation
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Keywords
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case <FT:5> | |
Glycoprotein | |
end case | |
case <FTTag:disulf> | |
Disulfide bond | |
end case |
Features
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From: PS50015 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | entry | exit | /note="Saposin B-type #" | |||||||||
DISULFID | 5 | 79 | disulf | C-x*-C | 1 | |||||||
DISULFID | 8 | 73 | disulf | C-x*-C | 2 | |||||||
DISULFID | 36 | 48 | disulf | C-x*-C | 3 | |||||||
CARBOHYD | 22 | 22 | /note="N-linked (GlcNAc...) asparagine" | N |
Additional information
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Size range | 35-160 amino acids |
Related rules |
None |
Fusion | None |
Repeats | 1-8 |
Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [69] All [ 69 ]
- Retrieve set of proteins with 3D structure for this domain