ProRule PRU00415

General rule information [?]

Accession PRU00415
Dates 7-APR-2005 (Created)
21-NOV-2019 (Last updated, Version 8)
Data class Domain;
Predictors PROSITE; PS50015; SAP_B
Name Saposin B-type domain
Function The saposin B-type domain is a ~80 amino acid domain present in saposins and related proteins that interact with lipids. In plant aspartic proteinases the two subdomains that are connected by disulfide bridges occur in inversed order, these "swapped" halves are called a "swaposin" domain.
Scope(s) Eukaryota
Example(s) P07602 (SAP_HUMAN);

Propagated annotation [?]

Keywords [?]

case <FT:5>
end case
case <FTTag:disulf>
Disulfide bond
end case

Features [?]

From: PS50015
Key From To Description Tag Condition FTGroup
DOMAIN entry exit /note="Saposin B-type #"
DISULFID 5 79 disulf C-x*-C 1
DISULFID 8 73 disulf C-x*-C 2
DISULFID 36 48 disulf C-x*-C 3
CARBOHYD 22 22 /note="N-linked (GlcNAc...) asparagine" N

Additional information [?]

Size range 35-160 amino acids
Related rules None
Fusion None
Repeats 1-8
Topology Undefined


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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UniProtKB rule member sequences [?]