ProRule logo

General rule information [?]

Accession PRU00416
Dates 6-APR-2005 (Created)
21-NOV-2019 (Last updated, Version 18)
Data class Domain
Predictors PROSITE; PS51093; PTS_EIIA_TYPE_1
Name PTS EIIA type-1 domain
Function Phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system.

Propagated annotation [?]

Comments [?]

case (<OC:Bacteria> or <OC:Archaea>) and <Feature:PS51093:53=H>
Domain The PTS EIIA type-1 domain is phosphorylated by phospho-HPr on a histidyl residue. Then, it transfers the phosphoryl group to the PTS EIIB type-1 domain.
end case

Gene Ontology [?]

case (<OC:Bacteria> or <OC:Archaea>) and <Feature:PS51093:53=H>
GO:0016740; Molecular function: transferase activity.

Keywords [?]

end case

Features [?]

From: PS51093
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       PTS EIIA type-1 #        
ACT_SITE     53     53       Tele-phosphohistidine intermediate; for EIIA activity     H  

Additional information [?]

Warning This domain can be found in other kind of proteins, mainly transcriptional regulators, in these cases it may serve as a regulatory function, through its phosphorylation activity, or as a simple phosphoryl donor. Check DE, KW and CC DOMAIN.
Size range 105 amino acids
Related rules none
Repeats 1
Topology Undefined
Example P09323 (PTW3C_ECOLI)


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]