We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00420
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00420
General rule information
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| Accession | PRU00420 |
| Dates | 06-APR-2005 (Created)
21-NOV-2019 (Last updated, Version 18) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51097; PTS_EIIA_TYPE_5 |
Name | PTS EIIA type-5 domain |
| Function | Phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system. |
| Scope(s) |
Bacteria Archaea |
| Example(s) | P05706; |
Propagated annotation
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Comments
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| case (<OC:Bacteria> or <OC:Archaea>) and <Feature:PS51097:41=H> | |
| DOMAIN | The EIIA type-5 domain is phosphorylated by phospho-HPr on a histidyl residue. Then, it transfers the phosphoryl group to the EIIB type-5 domain. |
| end case | |
Keywords
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Gene Ontology
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| case (<OCellular component:Bacteria> or <OC:Archaea>) and <Feature:PS51097:41=H> | |
| GO:0016740; Molecular function:transferase activity | |
Features
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| From: PS51097 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="PTS EIIA type-5 #" | |||||||||
| MOD_RES | 41 | 41 | /note="Phosphohistidine; by HPr" | H | ||||||||
Additional information
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| Size range | 114 amino acids |
| Related rules |
none |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [2] All [ 2 ]
- Retrieve set of proteins with 3D structure for this domain