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ProRule PRU00426


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PURL: https://purl.expasy.org/prosite/rule/PRU00426
General rule information [?]

Accession PRU00426
Dates 06-APR-2005 (Created)
21-NOV-2019 (Last updated, Version 22)
Data class Domain;
Predictors PROSITE; PS51103; PTS_EIIC_TYPE_1
Name PTS EIIC type-1 domain
Function Phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system.
Scope(s) Bacteria
Archaea
Example(s) P09323 (PTW3C_ECOLI);

Propagated annotation [?]

Comments [?]

case <OC:Bacteria> or <OC:Archaea>
DOMAINThe EIIC domain type-1 forms the PTS system translocation channel and contains the specific substrate-binding site.
end case
case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=2>
SUBCELLULAR LOCATIONCell inner membrane; Multi-pass membrane protein.
else case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=1>
SUBCELLULAR LOCATIONCell membrane; Multi-pass membrane protein.
else case <OC:Archaea> and defined <Property:Membrane>
SUBCELLULAR LOCATIONCell membrane; Multi-pass membrane protein.
else
SUBCELLULAR LOCATIONMembrane; Multi-pass membrane protein.
end case

Keywords [?]

case <OC:Bacteria> or <OC:Archaea>
Phosphotransferase system
Transport
Sugar transport
Transmembrane
Membrane
end case
case (<OC:Bacteria> or <OC:Archaea>) and defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case

Gene Ontology [?]

GO:0051119; Molecular function:sugar transmembrane transporter activity
case <OCellular component:Bacteria> and defined <Property:Membrane> and <Property:Membrane=2>
GO:0005886; Cellular component:plasma membrane
else case <OCellular component:Bacteria> and defined <Property:Membrane> and <Property:Membrane=1>
GO:0005886; Cellular component:plasma membrane
else case <OCellular component:Archaea> and defined <Property:Membrane>
GO:0005886; Cellular component:plasma membrane
else; https://www.ebi.ac.uk/QuickGO/term/else
GO:0016020; Cellular component:membrane
end case

Cross-references [?]

General Transmembrane; -; 6-10;

Features [?]

From: PS51103
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="PTS EIIC type-1 #"

Additional information [?]

Size range 369-380 amino acids
Related rules none
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]