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annotation rule: PRU00427

General rule information [?]

Accession PRU00427
Dates 6-APR-2005 (Created)
16-DEC-2016 (Last updated, Version 21)
Data class Domain
Predictors PROSITE; PS51104; PTS_EIIC_TYPE_2
Name PTS EIIC type-2 domain
Function Phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system.

Propagated annotation [?]


Comments [?]

case <OC:Bacteria> or <OC:Archaea>
Domain The EIIC type-2 domain forms the PTS system translocation channel and contains the specific substrate-binding site.
end case

case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=2>
Subcellular location Cell inner membrane; Multi-pass membrane protein.
else case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=1>
Subcellular location Cell membrane; Multi-pass membrane protein.
else case <OC:Archaea> and defined <Property:Membrane>
Subcellular location Cell membrane; Multi-pass membrane protein.
else
Subcellular location Membrane; Multi-pass membrane protein.
end case


Computed features [?]

General Transmembrane; -; 6-8; trigger=yes;

Gene Ontology [?]

GO:0051119; Molecular function: sugar transmembrane transporter activity.
case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=2>
GO:0005886; Cellular component: plasma membrane.
else case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=1>
GO:0005886; Cellular component: plasma membrane.
else case <OC:Archaea> and defined <Property:Membrane>
GO:0005886; Cellular component: plasma membrane.
else
GO:0016020; Cellular component: membrane.
end case


Keywords [?]

case <OC:Bacteria> or <OC:Archaea>
Transport
Sugar transport
Phosphotransferase system
Transmembrane
Membrane
end case

case (<OC:Bacteria> or <OC:Archaea>) and defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case


Features [?]

From: PS51104
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       PTS EIIC type-2 #        

Additional information [?]

Size range 352 amino acids
Related rules none
Repeats 1
Topology Undefined
Example P42956 (PTMCB_BACSU)
Scope
Bacteria
Archaea

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


View rule in raw text format (no links)


UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Archaea [1]
Bacteria [45]
All [ 46 ]