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|
| annotation rule: PRU00427 |
General rule information
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| Accession | PRU00427 |
| Dates | 6-APR-2005 (Created) 21-NOV-2019 (Last updated, Version 22) |
| Data class | Domain |
| Predictors | PROSITE; PS51104; PTS_EIIC_TYPE_2 |
| Name | PTS EIIC type-2 domain |
| Function | Phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system. |
Propagated annotation
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Comments
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case <OC:Bacteria> or <OC:Archaea>
| Domain | The EIIC type-2 domain forms the PTS system translocation channel and contains the specific substrate-binding site. |
end case
case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=2>
| Subcellular location | Cell inner membrane; Multi-pass membrane protein. |
else case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=1>
| Subcellular location | Cell membrane; Multi-pass membrane protein. |
else case <OC:Archaea> and defined <Property:Membrane>
| Subcellular location | Cell membrane; Multi-pass membrane protein. |
else
| Subcellular location | Membrane; Multi-pass membrane protein. |
end case
Computed features
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| General | Transmembrane; -; 6-8; trigger=yes; |
Gene Ontology
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GO:0051119; Molecular function: sugar transmembrane transporter activity.
case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=2>
GO:0005886; Cellular component: plasma membrane.
else case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=1>
GO:0005886; Cellular component: plasma membrane.
else case <OC:Archaea> and defined <Property:Membrane>
GO:0005886; Cellular component: plasma membrane.
else
GO:0016020; Cellular component: membrane.
end case
Keywords
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case <OC:Bacteria> or <OC:Archaea>
end case
case (<OC:Bacteria> or <OC:Archaea>) and defined <Property:Membrane> and <Property:Membrane=2>
end case
Features
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| From: PS51104 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | PTS EIIC type-2 # | |||||||||
Additional information
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| Size range | 352 amino acids |
| Related rules | none |
| Repeats | 1 |
| Topology | Undefined |
| Example | P42956 (PTMCB_BACSU) |
| Scope | Bacteria
Archaea |
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UniProtKB rule member sequences
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