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annotation rule: PRU00428

General rule information [?]

Accession PRU00428
Dates 6-APR-2005 (Created)
16-DEC-2016 (Last updated, Version 22)
Data class Domain
Predictors PROSITE; PS51105; PTS_EIIC_TYPE_3
Name PTS EIIC type-3 domain
Function Phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system.

Propagated annotation [?]


Comments [?]

case <OC:Bacteria> or <OC:Archaea>
Domain The EIIC type-3 domain forms the PTS system translocation channel and contains the specific substrate-binding site.
end case

case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=2>
Subcellular location Cell inner membrane; Multi-pass membrane protein.
else case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=1>
Subcellular location Cell membrane; Multi-pass membrane protein.
else case <OC:Archaea> and defined <Property:Membrane>
Subcellular location Cell membrane; Multi-pass membrane protein.
else
Subcellular location Membrane; Multi-pass membrane protein.
end case


Computed features [?]

General Transmembrane; -; 6-8; trigger=yes;

Gene Ontology [?]

GO:0051119; Molecular function: sugar transmembrane transporter activity.
case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=2>
GO:0005886; Cellular component: plasma membrane.
else case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=1>
GO:0005886; Cellular component: plasma membrane.
else case <OC:Archaea> and defined <Property:Membrane>
GO:0005886; Cellular component: plasma membrane.
else
GO:0016020; Cellular component: membrane.
end case


Keywords [?]

case <OC:Bacteria> or <OC:Archaea>
end case

case (<OC:Bacteria> or <OC:Archaea>) and defined <Property:Membrane> and <Property:Membrane=2>
end case


Features [?]

From: PS51105
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       PTS EIIC type-3 #        

Additional information [?]

Warning This domain can be found in association with EAL domain, in these cases it may have an other function. Check DE and CC DOMAIN.
Size range 407 amino acids
Related rules none
Repeats 1
Topology Undefined
Example Q45400 (PTEC_GEOSE)
Scope
Bacteria
Archaea

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.



UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Bacteria [18]