ProRule logo

General rule information [?]

Accession PRU00430
Dates 6-APR-2005 (Created)
21-NOV-2019 (Last updated, Version 25)
Data class Domain
Predictors PROSITE; PS51107; PTS_EIIC_TYPE_5
Name PTS EIIC type-5 domain
Function Phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system.

Propagated annotation [?]

Comments [?]

case <OC:Bacteria> or <OC:Archaea>
Domain The EIIC domain type-5 forms the PTS system translocation channel and contains the specific substrate-binding site.
end case

case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=2>
Subcellular location Cell inner membrane; Multi-pass membrane protein.
else case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=1> or <OC:Archaea> and defined <Property:Membrane>
Subcellular location Cell membrane; Multi-pass membrane protein.
Subcellular location Membrane; Multi-pass membrane protein.
end case

Computed features [?]

General Transmembrane; -; 6-8; trigger=yes;

Gene Ontology [?]

GO:0051119; Molecular function: sugar transmembrane transporter activity.
case (<OC:Bacteria> or <OC:Archaea>) and defined <Property:Membrane>
GO:0005886; Cellular component: plasma membrane.
GO:0016020; Cellular component: membrane.
end case

Keywords [?]

case <OC:Bacteria> or <OC:Archaea>
end case

case (<OC:Bacteria> or <OC:Archaea>) and defined <Property:Membrane> and <Property:Membrane=2>
end case

Features [?]

From: PS51107
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       PTS EIIC type-5 #        

Additional information [?]

Size range 187 amino acids
Related rules none
Repeats 1
Topology Undefined
Example O32332 (PTHC_CLOB8)


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Bacteria [3]