ProRule PRU00430
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PURL: https://purl.expasy.org/prosite/rule/PRU00430
General rule information
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| Accession | PRU00430 |
| Dates | 06-APR-2005 (Created)
21-NOV-2019 (Last updated, Version 26) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51107; PTS_EIIC_TYPE_5 |
Name | PTS EIIC type-5 domain |
| Function | Phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system. |
| Scope(s) |
Bacteria Archaea |
| Example(s) | O32332 (PTHC_CLOB8); |
Propagated annotation
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Comments
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| case <OC:Bacteria> or <OC:Archaea> | |
| DOMAIN | The EIIC domain type-5 forms the PTS system translocation channel and contains the specific substrate-binding site. |
| end case | |
| case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=2> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein. |
| else case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=1> or <OC:Archaea> and defined <Property:Membrane> | |
| SUBCELLULAR LOCATION | Cell membrane; Multi-pass membrane protein. |
| else | |
| SUBCELLULAR LOCATION | Membrane; Multi-pass membrane protein. |
| end case | |
Keywords
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| case <OC:Bacteria> or <OC:Archaea> | |
| Transport | |
| Sugar transport | |
| Phosphotransferase system | |
| Transmembrane | |
| Membrane | |
| end case | |
| case (<OC:Bacteria> or <OC:Archaea>) and defined <Property:Membrane> and <Property:Membrane=2> | |
| Cell inner membrane | |
| end case | |
Gene Ontology
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| GO:0051119; Molecular function:sugar transmembrane transporter activity | |
| case (<OCellular component:Bacteria> or <OC:Archaea>) and defined <Property:Membrane> | |
| GO:0005886; Cellular component:plasma membrane | |
| else; https://www.ebi.ac.uk/QuickGO/term/else | |
| GO:0016020; Cellular component:membrane | |
| end case | |
Cross-references
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| General | Transmembrane; -; 6-8; |
Features
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| From: PS51107 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="PTS EIIC type-5 #" | |||||||||
Additional information
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| Size range | 187 amino acids |
| Related rules |
none |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [3] All [ 3 ]
- Retrieve set of proteins with 3D structure for this domain