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| annotation rule: PRU00439 |
General rule information
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| Accession | PRU00439 |
| Dates | 6-MAY-2005 (Created) 26-JUL-2017 (Last updated, Version 5) |
| Data class | Domain |
| Predictors | PROSITE; PS51076; MH2 |
| Name | MAD homology domain 2 (MH2) |
| Function | The MH2 domain is responsible for transactivation and mediates phosphorylation-triggered heteromeric assembly between Smad4 and R-Smad. |
Propagated annotation
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Keywords
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case <Feature:PS51076:192-195=S-S-x-S>
end case
Features
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| From: PS51076 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | MH2 # | |||||||||
case <Feature:PS51076:192-195=S-S-x-S>
end case
Additional information
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| Size range | 160-235 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | Q99717 (SMAD5_HUMAN) |
| Scope | Eukaryota; Metazoa |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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UniProtKB/Swiss-Prot sets
Eukaryota [41]
- Retrieve set of proteins with 3D structure for this domain