We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00484
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00484
General rule information
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| Accession | PRU00484 |
| Dates | 26-AUG-2005 (Created)
27-JUN-2022 (Last updated, Version 9) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51139; GTF2I |
Name | GTF2I-like repeat |
| Function | The GTF2I-like repeats are specific to the TFII-I family of transcription factors and are likely to be involved in DNA binding. |
| Scope(s) |
Eukaryota Metazoa |
| Example(s) | Q9UHL9; |
Propagated annotation
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Comments
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| SUBCELLULAR LOCATION | Nucleus. |
| SIMILARITY | Belongs to the TFII-I family. |
Keywords
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Gene Ontology
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| GO:0003677; Molecular function:DNA binding |
| GO:0005634; Cellular component:nucleus |
| GO:0006355; Biological process:regulation of DNA-templated transcription |
| GO:0006351; Biological process:DNA-templated transcription |
Features
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| From: PS51139 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| REPEAT | from | to | /note="GTF2I-like #" | |||||||||
Additional information
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| Size range | 90-100 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-6 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [11] All [ 11 ]
- Retrieve set of proteins with 3D structure for this domain