We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00489
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00489
General rule information
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| Accession | PRU00489 |
| Dates | 20-OCT-2005 (Created)
20-OCT-2005 (Last updated, Version 2) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51143; MT_A70 |
Name | MT-A70-like family |
| Function | The MT-A70-like family comprises four subfamilies with varying degrees of interrelatedness. One subfamily is a small group of bacterial DNA: m6A MTases. The other three are paralogous eukaryotic lineages, two of which have not been associated with MTase activity but include proteins that regulate mRNA levels via unknown mechanisms apparently not involving methylation. |
| Scope(s) |
Eukaryota Bacteria |
| Example(s) | Q86U44; P25583; |
Propagated annotation
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Comments
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| SIMILARITY | Belongs to the MT-A70-like family. |
Features
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Additional information
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| Size range | 215-245 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [1] Eukaryota [26] All [ 27 ]
- Retrieve set of proteins with 3D structure for this domain