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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00500


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00500
General rule information [?]

Accession PRU00500
Dates 21-NOV-2005 (Created)
21-NOV-2019 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51162; THYROGLOBULIN_1_2
Name thyroglobulin type-1 domain
Function the Tg type-1 repeat is a module of about 70 amino acids present 11x in thyroglobulin (Tg) and as a single or repeated sequence in cysteine proteinase inhibitors and other proteins.
Scope(s) Eukaryota
Metazoa
Example(s) P24592;

Propagated annotation [?]

Keywords [?]

case <FTTag:disulf>
Disulfide bond
end case

Features [?]

From: PS51162
Key From To Description Tag Condition FTGroup
DOMAIN entry exit /note="Thyroglobulin type-1 #"
DISULFID 4 23 disulf C-x*-C
DISULFID 34 41 disulf C-x*-C
DISULFID 43 63 disulf C-x*-C

Additional information [?]

Size range 40-210 amino acids
Related rules None
Fusion None
Repeats 1-11
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]