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ProRule PRU00502


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PURL: https://purl.expasy.org/prosite/rule/PRU00502
General rule information [?]

Accession PRU00502
Dates 23-NOV-2005 (Created)
19-NOV-2022 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS50271; ZF_UBP
Name UBP-type zinc finger
Function ubiquitin binding domain
Scope(s) Eukaryota
Example(s) Q5DU02 (UBP22_MOUSE);

Propagated annotation [?]

Keywords [?]

Metal-binding
Zinc
end case
Zinc-finger

Gene Ontology [?]

case (<Feature:PS50271:3=[CH]> and <Feature:PS50271:5=[HC]> and <Feature:PS50271:76=[CH]> and <Feature:PS50271:79=[CH]>) or (<Feature:PS50271:25=[CH]> and <Feature:PS50271:28=[CH]> and <Feature:PS50271:46=[CH]> and <Feature:PS50271:53=[HC]>) or (<Feature:PS50271:38=[CH]> and <Feature:PS50271:41=[CH]> and <Feature:PS50271:57=[HC]> and <Feature:PS50271:63=[HC]>)
GO:0046872; Molecular function:metal ion binding

Features [?]

From: PS50271
Key From To Description Tag Condition FTGroup
case (<Feature:PS50271:3=C> and <Feature:PS50271:5=H> and <Feature:PS50271:76=C> and <Feature:PS50271:79=C>) and (<Feature:PS50271:25=C> and <Feature:PS50271:28=C> and <Feature:PS50271:46=C> and <Feature:PS50271:53=H>) and (<Feature:PS50271:38=C> and <Feature:PS50271:41=C> and <Feature:PS50271:57=H> and <Feature:PS50271:63=H>)
ZN_FING from to /note="UBP-type #"
else case (<Feature:PS50271:3=[CH]> and <Feature:PS50271:5=[HC]> and <Feature:PS50271:76=[CH]> and <Feature:PS50271:79=[CH]>) and (<Feature:PS50271:25=[CH]> and <Feature:PS50271:28=[CH]> and <Feature:PS50271:46=[CH]> and <Feature:PS50271:53=[HC]>) and (<Feature:PS50271:38=[CH]> and <Feature:PS50271:41=[CH]> and <Feature:PS50271:57=[HC]> and <Feature:PS50271:63=[HC]>)
ZN_FING from to /note="UBP-type #; atypical"
else
ZN_FING from to /note="UBP-type #; degenerate"
end case
BINDING 3 3 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 5 5 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 25 25 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 [CH] 2
BINDING 28 28 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 [CH] 2
BINDING 38 38 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#3"		 [CH] 3
BINDING 41 41 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#3"		 [CH] 3
BINDING 46 46 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 [CH] 2
BINDING 53 53 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 [CH] 2
BINDING 57 57 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#3"		 [CH] 3
BINDING 63 63 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#3"		 [CH] 3
BINDING 76 76 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 79 79 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1

Additional information [?]

Size range 59-76 amino acids
Related rules None
Fusion None
Repeats 1-2
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]