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| annotation rule: PRU00512 |
General rule information
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| Accession | PRU00512 |
| Dates | 24-NOV-2005 (Created) 27-JUN-2022 (Last updated, Version 11) |
| Data class | Domain |
| Predictors | PROSITE; PS51156; ELM2 |
| Name | ELM2 domain |
| Function | The ELM2 (EGL-27 and MTA1 homology) domain has been shown to function as a transcriptional repression domain through recruitment of HDAC activity. |
Propagated annotation
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Comments
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| Subcellular location | Nucleus. |
Gene Ontology
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GO:0005634; Cellular component: nucleus.
GO:0006355; Biological process: regulation of DNA-templated transcription.
GO:0006351; Biological process: DNA-templated transcription.
GO:0006355; Biological process: regulation of DNA-templated transcription.
GO:0006351; Biological process: DNA-templated transcription.
Keywords
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Features
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| From: PS51156 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | ELM2 # | |||||||||
Additional information
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| Size range | 85-115 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Not cytoplasmic |
| Example | Q9P2K3 (RCOR3_HUMAN) |
| Scope | Eukaryota |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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UniProtKB/Swiss-Prot sets
Eukaryota [46]
- Retrieve set of proteins with 3D structure for this domain