ProRule PRU00512

General rule information [?]

Accession PRU00512
Dates 24-NOV-2005 (Created)
27-JUN-2022 (Last updated, Version 11)
Data class Domain;
Predictors PROSITE; PS51156; ELM2
Name ELM2 domain
Function The ELM2 (EGL-27 and MTA1 homology) domain has been shown to function as a transcriptional repression domain through recruitment of HDAC activity.
Scope(s) Eukaryota
Example(s) Q9P2K3 (RCOR3_HUMAN);

Propagated annotation [?]

Comments [?]


Keywords [?]

Gene Ontology [?]

GO:0005634; Cellular component:nucleus
GO:0006355; Biological process:regulation of DNA-templated transcription
GO:0006351; Biological process:DNA-templated transcription

Features [?]

From: PS51156
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="ELM2 #"

Additional information [?]

Size range 85-115 amino acids
Related rules None
Fusion None
Repeats 1
Topology Not cytoplasmic


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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UniProtKB rule member sequences [?]