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annotation rule: PRU00512

General rule information [?]

Accession PRU00512
Dates 24-NOV-2005 (Created)
27-JUN-2022 (Last updated, Version 11)
Data class Domain
Predictors PROSITE; PS51156; ELM2
Name ELM2 domain
Function The ELM2 (EGL-27 and MTA1 homology) domain has been shown to function as a transcriptional repression domain through recruitment of HDAC activity.

Propagated annotation [?]

Comments [?]

Subcellular location Nucleus.

Gene Ontology [?]

GO:0005634; Cellular component: nucleus.
GO:0006355; Biological process: regulation of DNA-templated transcription.
GO:0006351; Biological process: DNA-templated transcription.

Keywords [?]

Features [?]

From: PS51156
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       ELM2 #        

Additional information [?]

Size range 85-115 amino acids
Related rules None
Repeats 1
Topology Not cytoplasmic
Example Q9P2K3 (RCOR3_HUMAN)


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]