We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00516
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00516
General rule information
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| Accession | PRU00516 |
| Dates | 09-DEC-2005 (Created)
30-SEP-2022 (Last updated, Version 11) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51169; CHORISMATE_MUT_3 |
Name | chorismate mutase domain |
| Function | Chorismate mutase is a regulatory enzyme required for biosynthesis of the aromatic amino acids phenylalanine and tyrosine. |
| Scope(s) |
Eukaryota Fungi Viridiplantae |
| Example(s) | O13739; |
Propagated annotation
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Identifier, protein and gene names
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| Protein name | + RecName: EC=5.4.99.5; |
Comments
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| CATALYTIC ACTIVITY | Reaction=chorismate = prephenate; Xref=Rhea:RHEA:13897, ChEBI:CHEBI:29748, ChEBI:CHEBI:29934; EC=5.4.99.5; |
Keywords
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Gene Ontology
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| GO:0003824; Molecular function:catalytic activity |
| GO:0009073; Biological process:aromatic amino acid family biosynthetic process |
| GO:0008652; Biological process:amino acid biosynthetic process |
| GO:0016853; Molecular function:isomerase activity |
Features
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| From: PS51169 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Chorismate mutase #" | |||||||||
Additional information
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| Size range | 240-270 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [13] All [ 13 ]
- Retrieve set of proteins with 3D structure for this domain