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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00519


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00519
General rule information [?]

Accession PRU00519
Dates 12-DEC-2005 (Created)
21-NOV-2019 (Last updated, Version 5)
Data class Domain;
Predictors PROSITE; PS50040; EF1G_C
Name Elongation factor 1 (EF-1) gamma C-terminal domain
Function The eukaryotic elongation factor 1 (EF-1) gamma chain is a protein of about 410 to 440 residues, which consists of two independent domains, a glutathione S-transferase (GST) homologous N-terminal region responsible for the interaction with EF-1 alpha and a highly conserved exceptionally protease resistant ~160 residue C-terminal domain.
Scope(s) Eukaryota
Example(s) P26641;

Propagated annotation [?]

Keywords [?]

Elongation factor
Protein biosynthesis

Gene Ontology [?]

GO:0006412; Biological process:translation
GO:0003746; Molecular function:translation elongation factor activity

Features [?]

From: PS50040
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="EF-1-gamma C-terminal #"

Additional information [?]

Size range 155-165 amino acids
Related rules None
Fusion None
Repeats 1
Topology Cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]