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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00521


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00521
General rule information [?]

Accession PRU00521
Dates 15-DEC-2005 (Created)
21-NOV-2019 (Last updated, Version 11)
Data class Domain;
Predictors PROSITE; PS50262; G_PROTEIN_RECEP_F1_2
Name G-protein coupled receptors family 1
Function transduces extracellular signals by interaction with guanine nucleotide-binding (G) proteins.
Scope(s) Eukaryota
Example(s) Q9N298;

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the G-protein coupled receptor 1 family.

Keywords [?]

G-protein coupled receptor
Membrane
Receptor
Transducer
case <FTTag:disulf>
Disulfide bond
end case

Gene Ontology [?]

GO:0004930; Molecular function:G protein-coupled receptor activity
GO:0007186; Molecular function:G protein-coupled receptor signaling pathway
GO:0007165; Biological process:signal transduction

Cross-references [?]

PROSITE PS00237; G_PROTEIN_RECEP_F1_1; 1;

Features [?]

From: PS50262
Key From To Description Tag Condition FTGroup
DISULFID 57 136 disulf C-x*-C
DISULFID 129 135 disulf C-x*-C

Additional information [?]

Size range 200-400 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]