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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00529


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00529
General rule information [?]

Accession PRU00529
Dates 25-JAN-2006 (Created)
21-NOV-2019 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS51165; THUMP
Name THUMP domain
Function The THUMP (after thiouridine synthases, RNA methylases and pseudouridine synthases) domain is a module of 100-110 amino acid residues which is involved RNA metabolism. THUMP is an ancient domain with predicted RNA-binding capacity that probably functions by delivering a variety of RNA modification enzymes to their targets.
Scope(s) Eukaryota
Bacteria
Archaea
Example(s) P53072;

Propagated annotation [?]

Keywords [?]

RNA-binding

Gene Ontology [?]

GO:0003723; Molecular function:RNA binding

Features [?]

From: PS51165
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="THUMP #"

Additional information [?]

Size range 90-120 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]