ProRule PRU00529
General rule information
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| Accession | PRU00529 |
| Dates | 25-JAN-2006 (Created)
21-NOV-2019 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51165; THUMP |
Name | THUMP domain |
| Function | The THUMP (after thiouridine synthases, RNA methylases and pseudouridine synthases) domain is a module of 100-110 amino acid residues which is involved RNA metabolism. THUMP is an ancient domain with predicted RNA-binding capacity that probably functions by delivering a variety of RNA modification enzymes to their targets. |
| Scope(s) |
Eukaryota Bacteria Archaea |
| Example(s) | P53072 (TAN1_YEAST); |
Propagated annotation
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Keywords
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Gene Ontology
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| GO:0003723; Molecular function:RNA binding |
Features
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| From: PS51165 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="THUMP #" | |||||||||
Additional information
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| Size range | 90-120 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Archaea [55] Bacteria [432] Eukaryota [11] All [ 498 ]
- Retrieve set of proteins with 3D structure for this domain