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ProRule PRU00530


General rule information [?]

PURL https://purl.expasy.org/prosite/rule/PRU00530
Accession PRU00530
Dates 27-JAN-2006 (Created)
27-JUN-2022 (Last updated, Version 11)
Data class Domain;
Predictors PROSITE; PS51179; POU_3
Name POU-specific (POUs) domain
Function The POUs domain is always found in association with a POU- homeodomain, and both are required for high affinity and sequence-specific DNA binding.
Scope(s) Eukaryota
Metazoa
Example(s) P24350 (IPOU_DROME);

Propagated annotation [?]

Comments [?]

SUBCELLULAR LOCATIONNucleus.

Keywords [?]

DNA-binding
Nucleus
Transcription
Transcription regulation

Gene Ontology [?]

GO:0003677; Molecular function:DNA binding
GO:0005634; Cellular component:nucleus
GO:0006355; Biological process:regulation of DNA-templated transcription
GO:0006351; Biological process:DNA-templated transcription

Cross-references [?]

PROSITE PS00035; POU_1; 1;
PROSITE PS00465; POU_2; 1;

Features [?]

From: PS51179
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="POU-specific #"

Additional information [?]

Size range 70-115 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

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UniProtKB rule member sequences [?]