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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00536


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00536
General rule information [?]

Accession PRU00536
Dates 20-MAR-2006 (Created)
03-JUN-2021 (Last updated, Version 7)
Data class Protein;
Predictors PROSITE; PS51191; FEMABX
Name FemABX peptidyl transferase family
Function FemABX peptidyl transferases catalyze the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan using aminoacyl-tRNA as the amino acid donor, a reaction involved in the synthesis of the bacterial cell wall.
Scope(s) Bacteria
Example(s) P0A0A5;

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name + RecName: EC=2.3.2.-;

Comments [?]

SIMILARITYBelongs to the femABX family.

Keywords [?]

Peptidoglycan synthesis
Cell shape
Cell wall
Acyltransferase
Transferase

Gene Ontology [?]

GO:0009252; Biological process:peptidoglycan biosynthetic process
GO:0000902; Biological process:cell morphogenesis
GO:0016755; Molecular function:aminoacyltransferase activity

Features [?]


Additional information [?]

Size range 400-420 amino acids
Related rules PRU00532
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]