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annotation rule: PRU00538

General rule information [?]

Accession PRU00538
Dates 16-MAR-2006 (Created)
21-NOV-2019 (Last updated, Version 5)
Data class Domain
Predictors PROSITE; PS51184; JMJC
Name JmjC domain
Function the JmjC domain is found in organisms from bacteria to human and has been shown to function in a histone demethylation mechanism that is conserved from yeast to human.

Propagated annotation [?]

Gene Ontology [?]

case <FTGroup:1>
GO:0046872; Molecular function: metal ion binding.

Keywords [?]

end case

Features [?]

From: PS51184
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       JmjC #        
METAL     47     47       Iron; catalytic     H   1
METAL     49     49       Iron; catalytic     [DE]   1
METAL     129     129       Iron; catalytic     [HY]   1

Additional information [?]

Size range 120-230 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q9Y4C1 (KDM3A_HUMAN)


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]