ProRule PRU00538
General rule information
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Accession | PRU00538 |
Dates | 16-MAR-2006 (Created)
19-NOV-2022 (Last updated, Version 7) |
Data class | Domain; |
Predictors |
PROSITE; PS51184; JMJC |
Name | JmjC domain |
Function | the JmjC domain is found in organisms from bacteria to human and has been shown to function in a histone demethylation mechanism that is conserved from yeast to human. |
Scope(s) |
Eukaryota Bacteria Viruses |
Example(s) | Q9Y4C1 (KDM3A_HUMAN); |
Propagated annotation
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Keywords
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case <FTGroup:1> | |
Iron | |
Metal-binding | |
end case |
Gene Ontology
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case <FTGroup:1> | |
GO:0046872; Molecular function:metal ion binding | |
end case |
Features
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From: PS51184 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | /note="JmjC #" | |||||||||
BINDING | 47 | 47 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_note="catalytic" |
H | 1 | |||||||
BINDING | 49 | 49 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_note="catalytic" |
[DE] | 1 | |||||||
BINDING | 129 | 129 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_note="catalytic" |
[HY] | 1 |
Additional information
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Size range | 120-230 amino acids |
Related rules |
None |
Fusion | None |
Repeats | 1 |
Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [3] Eukaryota [212] Viruses [1] All [ 216 ]
- Retrieve set of proteins with 3D structure for this domain