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ProRule PRU00538


General rule information [?]

Accession PRU00538
Dates 16-MAR-2006 (Created)
19-NOV-2022 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51184; JMJC
Name JmjC domain
Function the JmjC domain is found in organisms from bacteria to human and has been shown to function in a histone demethylation mechanism that is conserved from yeast to human.
Scope(s) Eukaryota
Bacteria
Viruses
Example(s) Q9Y4C1 (KDM3A_HUMAN);

Propagated annotation [?]

Keywords [?]

case <FTGroup:1>
Iron
Metal-binding
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0046872; Molecular function:metal ion binding
end case

Features [?]

From: PS51184
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="JmjC #"
BINDING 47 47 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_note="catalytic"
H 1
BINDING 49 49 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_note="catalytic"
[DE] 1
BINDING 129 129 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_note="catalytic"
[HY] 1

Additional information [?]

Size range 120-230 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



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UniProtKB rule member sequences [?]