annotation rule: PRU00538

General rule information [?]

Accession PRU00538
Dates 16-MAR-2006 (Created)
16-DEC-2016 (Last updated, Version 4)
Data class Domain
Predictors PROSITE; PS51184; JMJC
Name JmjC domain
Function the JmjC domain is found in organisms from bacteria to human and has been shown to function in a histone demethylation mechanism that is conserved from yeast to human.

Propagated annotation [?]


Gene Ontology [?]

case <FTGroup:1>
GO:0046872; Molecular function: metal ion binding.

Keywords [?]

Iron
Metal-binding
end case


Features [?]

From: PS51184
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       JmjC #        
METAL     47     47       Iron; catalytic     H   1
METAL     49     49       Iron; catalytic     [DE]   1
METAL     129     129       Iron; catalytic     [HY]   1

Additional information [?]

Size range 120-230 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q9Y4C1 (KDM3A_HUMAN)
Scope Eukaryota
Bacteria
Viruses

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.


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UniProtKB rule member sequences [?]