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annotation rule: PRU00550

General rule information [?]

Accession PRU00550
Dates 9-MAY-2006 (Created)
21-NOV-2019 (Last updated, Version 3)
Data class Domain
Predictors PROSITE; PS51205; VPS9
Name VPS9 domain
Function The VPS9 domain is a GDP-GTP exchange factor (GEF) domain that catalyzes nucleotide exchange on Rab5, which activates this Rab GTPase.

Propagated annotation [?]


Gene Ontology [?]

GO:0005096; Molecular function: GTPase activator activity.

Keywords [?]

GTPase activation

Features [?]

From: PS51205
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       VPS9 #        

Additional information [?]

Size range 130-170 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q8TB24 (RIN3_HUMAN)
Scope
Eukaryota

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]