ProRule PRU00550

General rule information [?]

Accession PRU00550
Dates 9-MAY-2006 (Created)
21-NOV-2019 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51205; VPS9
Name VPS9 domain
Function The VPS9 domain is a GDP-GTP exchange factor (GEF) domain that catalyzes nucleotide exchange on Rab5, which activates this Rab GTPase.
Scope(s) Eukaryota
Example(s) Q8TB24 (RIN3_HUMAN);

Propagated annotation [?]

Keywords [?]

Gene Ontology [?]

GO:0005096; Molecular function:GTPase activator activity

Features [?]

From: PS51205
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="VPS9 #"

Additional information [?]

Size range 130-170 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]