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| annotation rule: PRU00550 |
General rule information
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| Accession | PRU00550 |
| Dates | 9-MAY-2006 (Created) 21-NOV-2019 (Last updated, Version 3) |
| Data class | Domain |
| Predictors | PROSITE; PS51205; VPS9 |
| Name | VPS9 domain |
| Function | The VPS9 domain is a GDP-GTP exchange factor (GEF) domain that catalyzes nucleotide exchange on Rab5, which activates this Rab GTPase. |
Propagated annotation
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Gene Ontology
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GO:0005096; Molecular function: GTPase activator activity.
Keywords
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Features
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| From: PS51205 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | VPS9 # | |||||||||
Additional information
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| Size range | 130-170 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | Q8TB24 (RIN3_HUMAN) |
| Scope | Eukaryota |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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UniProtKB/Swiss-Prot sets
Eukaryota [53]
- Retrieve set of proteins with 3D structure for this domain