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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00555


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00555
General rule information [?]

Accession PRU00555
Dates 22-MAY-2006 (Created)
21-NOV-2019 (Last updated, Version 8)
Data class Domain;
Predictors PROSITE; PS51210; PLA2C
Name PLA2c domain
Function The PLA2c domain is the catalytic lipase domain in cytosolic phospholipase A2 (cPLA2) (EC 3.1.1.4) and lysophospholipase or phospholipase B (PLB) (EC 3.1.1.5) of vertebrates and fungi.
Scope(s) Eukaryota
Example(s) Q9P8P2;

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name + RecName: EC=3.1.1.-;

Keywords [?]

Hydrolase
Lipid degradation
Lipid metabolism

Gene Ontology [?]

GO:0016787; Molecular function:hydrolase activity
GO:0016042; Biological process:lipid catabolic process

Features [?]

From: PS51210
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="PLA2c #"

Additional information [?]

Size range 520-610 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]