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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00557


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00557
General rule information [?]

Accession PRU00557
Dates 24-MAY-2006 (Created)
21-NOV-2019 (Last updated, Version 6)
Data class Domain;
Predictors PROSITE; PS51211; VITELLOGENIN
Name Vitellogenin domain
Function The vitellogenin (VTG) protein, a major lipoprotein in many oviparous animals, is a precursor of a lipid-binding product found in the yolk of egg-laying animals, and involved in lipid and metal storage. At the N-terminal, it contains a sequence of about 670 amino acids (LV1n chain), which is also conserved in other large lipoproteins, such as microsomal triglyceride transfer protein (MTP) and apolipoprotein B-100 (apoB)
Scope(s) Eukaryota
Example(s) Q91062;

Propagated annotation [?]

Keywords [?]

case <FTTag:disulf>
Disulfide bond
end case

Cross-references [?]

PROSITE PS51211; VITELLOGENIN; 1;

Features [?]

From: PS51211
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Vitellogenin #"
DISULFID 139 165 disulf C-x*-C
DISULFID 181 184 disulf C-x*-C
DISULFID 409 414 disulf C-x*-C

Additional information [?]

Size range 600-660 amino acids
Related rules none
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]