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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00560


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00560
General rule information [?]

Accession PRU00560
Dates 19-DEC-2006 (Created)
19-NOV-2022 (Last updated, Version 10)
Data class Domain;
Predictors PROSITE; PS51198; UVRD_HELICASE_ATP_BIND
Name UvrD helicase ATP-binding domain
Function UvrD helicase unwind DNA with a 3'-5' polarity
Scope(s) Eukaryota
Bacteria
Archaea
Viruses
Example(s) P64319;

Propagated annotation [?]

Keywords [?]

ATP-binding
Helicase
Hydrolase
Nucleotide-binding

Gene Ontology [?]

GO:0004386; Molecular function:helicase activity
GO:0005524; Molecular function:ATP binding
GO:0016787; Molecular function:hydrolase activity
GO:0000166; Molecular function:nucleotide binding

Features [?]

From: PS51198
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="UvrD-like helicase ATP-binding #"
BINDING 22 29 /ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"

Additional information [?]

Size range 200-600 amino acids
Related rules None
Fusion None
Repeats 2
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]