We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00564
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00564
General rule information
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| Accession | PRU00564 |
| Dates | 24-JUL-2006 (Created)
21-NOV-2019 (Last updated, Version 9) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51219; DPCK |
Name | Dephospho-CoA kinase (DPCK) domain |
| Function | Dephospho-coenzyme A kinase (DPCK) (EC 2.7.1.24) catalyzes the final step in coenzyme A (CoA) biosynthesis, the phosphorylation of the 3'-hydroxyl group of ribose using ATP as a phosphate donor. |
| Scope(s) |
Eukaryota Bacteria |
| Example(s) | P0A6I9; |
Propagated annotation
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Identifier, protein and gene names
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| Protein name | AltName: Full=Dephospho-CoA kinase; EC=2.7.1.24; AltName: Full=Dephosphocoenzyme A kinase; |
Comments
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| CATALYTIC ACTIVITY | Reaction=3'-dephospho-CoA + ATP = ADP + CoA + H(+); Xref=Rhea:RHEA:18245, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:57287, ChEBI:CHEBI:57328, ChEBI:CHEBI:456216; EC=2.7.1.24; |
Keywords
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Gene Ontology
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| GO:0015937; Biological process:coenzyme A biosynthetic process |
| GO:0016301; Molecular function:kinase activity |
| GO:0016740; Molecular function:transferase activity |
Cross-references
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| PROSITE | PS00017; ATP_GTP_A; 1; |
Features
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| From: PS51219 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="DPCK #" | |||||||||
Additional information
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| Size range | 175-235 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [265] Eukaryota [14] All [ 279 ]
- Retrieve set of proteins with 3D structure for this domain