ProRule PRU00581

General rule information [?]

Accession PRU00581
Dates 17-OCT-2006 (Created)
30-SEP-2022 (Last updated, Version 6)
Data class Domain;
Predictors PROSITE; PS51225; MARVEL
Name MARVEL domain
Function The ~130-residue MAL and related proteins for vesicle trafficking and membrane link (MARVEL) domain is a module with a four transmembrane-helix architecture that has been identified in proteins of the myelin and lymphocyte (MAL), physins, gyrins and occludin families.
Scope(s) Eukaryota
Example(s) Q8IZ96 (CKLF1_HUMAN);

Propagated annotation [?]

Keywords [?]

Gene Ontology [?]

GO:0016020; Cellular component:membrane

Cross-references [?]

General Transmembrane; -; 4;

Features [?]

From: PS51225
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="MARVEL #"

Additional information [?]

Size range 115-215 amino acids
Related rules None
Fusion None
Repeats 1-2
Topology Not cytoplasmic


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UniProtKB rule member sequences [?]