ProRule PRU00581
General rule information
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| Accession | PRU00581 |
| Dates | 17-OCT-2006 (Created)
30-SEP-2022 (Last updated, Version 6) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51225; MARVEL |
Name | MARVEL domain |
| Function | The ~130-residue MAL and related proteins for vesicle trafficking and membrane link (MARVEL) domain is a module with a four transmembrane-helix architecture that has been identified in proteins of the myelin and lymphocyte (MAL), physins, gyrins and occludin families. |
| Scope(s) |
Eukaryota Metazoa |
| Example(s) | Q8IZ96 (CKLF1_HUMAN); |
Propagated annotation
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Keywords
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Gene Ontology
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| GO:0016020; Cellular component:membrane |
Cross-references
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| General | Transmembrane; -; 4; |
Features
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| From: PS51225 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="MARVEL #" | |||||||||
Additional information
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| Size range | 115-215 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-2 |
| Topology | Not cytoplasmic |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [105] All [ 105 ]
- Retrieve set of proteins with 3D structure for this domain