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annotation rule: PRU00581

General rule information [?]

Accession PRU00581
Dates 17-OCT-2006 (Created)
7-JAN-2017 (Last updated, Version 4)
Data class Domain
Predictors PROSITE; PS51225; MARVEL
Name MARVEL domain
Function The ~130-residue MAL and related proteins for vesicle trafficking and membrane link (MARVEL) domain is a module with a four transmembrane-helix architecture that has been identified in proteins of the myelin and lymphocyte (MAL), physins, gyrins and occludin families.

Propagated annotation [?]


Computed features [?]

General Transmembrane; -; 4;

Gene Ontology [?]

GO:0016020; Cellular component: membrane.
GO:0016021; Cellular component: integral component of membrane.

Keywords [?]


Features [?]

From: PS51225
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       MARVEL #        

Additional information [?]

Size range 115-215 amino acids
Related rules None
Repeats 1-2
Topology Not cytoplasmic
Example Q8IZ96 (CKLF1_HUMAN)
Scope
Eukaryota; Metazoa

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.



UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Eukaryota [105]