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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00588


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00588
General rule information [?]

Accession PRU00588
Dates 16-JAN-2007 (Created)
21-NOV-2019 (Last updated, Version 5)
Data class Domain;
Predictors PROSITE; PS51259; MHD2
Name Munc13-homology domain 2 (MHD2)
Function The MHD2 domain is present in a wide variety of proteins from Arabidopsis thaliana, C. elegans, Drosophila melanogaster, mouse, rat and human, some of which may function in a Munc13-like manner to regulate membrane trafficking.
Scope(s) Eukaryota
Example(s) P27715;

Propagated annotation [?]

Features [?]

From: PS51259
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="MHD2 #"

Additional information [?]

Size range 105-170 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]