We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00596
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00596
General rule information
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| Accession | PRU00596 |
| Dates | 17-OCT-2006 (Created)
25-APR-2024 (Last updated, Version 8) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51199; SF4_HELICASE |
Name | SF4 helicase domain |
| Function | Undefined |
| Scope(s) |
Eukaryota Bacteria Viruses |
| Example(s) | P57611; |
Propagated annotation
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Keywords
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Gene Ontology
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| GO:0005524; Molecular function:ATP binding |
| GO:0006260; Biological process:DNA replication |
| GO:0003677; Molecular function:DNA binding |
| GO:0004386; Molecular function:helicase activity |
| GO:0016787; Molecular function:hydrolase activity |
| GO:0000166; Molecular function:nucleotide binding |
| GO:0006269; Biological process:DNA replication, synthesis of primer |
| GO:0005658; Cellular component:alpha DNA polymerase:primase complex |
Features
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| From: PS51199 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="SF4 helicase #" | |||||||||
| BINDING | 32 | 39 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
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Additional information
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| Size range | 250-298 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-2 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [36] Eukaryota [9] Viruses [4] All [ 49 ]
- Retrieve set of proteins with 3D structure for this domain