ProRule PRU00599
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU00599 |
| Accession | PRU00599 |
| Dates | 19-JAN-2007 (Created)
21-NOV-2019 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51263; ADF_H |
Name | ADF-H domain |
| Function | The actin-depolymerizing factor homology (ADF-H) domain is an ~150- amino acid motif present in three phylogenetically distinct classes of eukaryotic actin-binding proteins that all appear to use the ADF-H domain for their interactions with actin. |
| Scope(s) |
Eukaryota |
| Example(s) | P23528 (COF1_HUMAN); |
Propagated annotation
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Keywords
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Gene Ontology
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| GO:0003779; Molecular function:actin binding |
Features
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| From: PS51263 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="ADF-H #" | |||||||||
Additional information
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| Size range | 125-160 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-3 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [138] All [ 138 ]
- Retrieve set of proteins with 3D structure for this domain