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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00599


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00599
General rule information [?]

Accession PRU00599
Dates 19-JAN-2007 (Created)
21-NOV-2019 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS51263; ADF_H
Name ADF-H domain
Function The actin-depolymerizing factor homology (ADF-H) domain is an ~150- amino acid motif present in three phylogenetically distinct classes of eukaryotic actin-binding proteins that all appear to use the ADF-H domain for their interactions with actin.
Scope(s) Eukaryota
Example(s) P23528;

Propagated annotation [?]

Keywords [?]

Actin-binding

Gene Ontology [?]

GO:0003779; Molecular function:actin binding

Features [?]

From: PS51263
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="ADF-H #"

Additional information [?]

Size range 125-160 amino acids
Related rules None
Fusion None
Repeats 1-3
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]