We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00605
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00605
General rule information
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| Accession | PRU00605 |
| Dates | 08-DEC-2006 (Created)
21-NOV-2019 (Last updated, Version 9) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51273; GATASE_TYPE_1 |
Name | Glutamine amidotransferase (GATase) type 1 domain |
| Function | GATases are enzymes that catalyze the removal of the ammonia group from glutamine and transfer this group to a substrate to form a new carbon-nitrogen group. In the GATase type 1 domain the catalytic cysteine is located in a triad of Cys-His-Glu that forms the active site. |
| Scope(s) |
Bacteria Eukaryota Archaea Viruses |
| Example(s) | P0A6F1; |
Propagated annotation
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Keywords
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| Glutamine amidotransferase | |
| end case | |
Gene Ontology
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| case <FTGroup:1> | |
| GO:0006541; Biological process:glutamine metabolic process | |
Features
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| From: PS51273 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Glutamine amidotransferase type-1 #" | |||||||||
| ACT_SITE | 77 | 77 | /note="Nucleophile" | C | 1 | |||||||
| ACT_SITE | 163 | 163 | H | 1 | ||||||||
| ACT_SITE | 165 | 165 | E | 1 | ||||||||
Additional information
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| Size range | 165-300 amino acids |
| Related rules |
PRU00480 PRU00606 PRU00607 PRU00608 |
| Fusion | None |
| Repeats | 1-2 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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