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PRU00605


General rule information [?]

Accession PRU00605
Dates 8-DEC-2006 (Created)
21-NOV-2019 (Last updated, Version 8)
Data class Domain
Predictors PROSITE; PS51273; GATASE_TYPE_1
Names Glutamine amidotransferase (GATase) type 1 domain; trpG-type gatase; GATases class-I; triad type GATase
Function GATases are enzymes that catalyze the removal of the ammonia group from glutamine and transfer this group to a substrate to form a new carbon-nitrogen group. In the GATase type 1 domain the catalytic cysteine is located in a triad of Cys-His-Glu that forms the active site.

Propagated annotation [?]


Gene Ontology [?]

case <FTGroup:1>
GO:0006541; Biological process: glutamine metabolic process.

Keywords [?]

end case


Features [?]

From: PS51273
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Glutamine amidotransferase type-1 #        
ACT_SITE     77     77       Nucleophile     C   1
ACT_SITE     163     163             H   1
ACT_SITE     165     165             E   1

Additional information [?]

Warning Proteins with this domain may have different enzymatic activities (EC 2.4.2.-, EC 2.4.2.14, EC 4.1.3.27, EC 4.1.3.-, EC 6.3.4.2, EC 6.3.5.2, EC 6.3.5.5 or EC 6.3.5.3).
Size range 165-300 amino acids
Related rules PRU00480; PRU00606; PRU00607; PRU00608
Repeats 1-2
Topology Undefined
Example P0A6F1 (CARA_ECOLI)
Scope
Bacteria
Eukaryota
Archaea
Viruses

Copyright

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UniProtKB rule member sequences [?]