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annotation rule: PRU00611

General rule information [?]

Accession PRU00611
Dates 19-JAN-2007 (Created)
21-NOV-2019 (Last updated, Version 7)
Data class Domain
Predictors PROSITE; PS51281; TAP_C
Name TAP C-terminal (TAP-C) domain
Function Members of the NXF family of shuttling transport receptors for nuclear export of mRNA have a modular structure. Their most C-terminal TAP-C domain is important for binding to FG repeat-containing nuclear pore proteins (FG-nucleoporins) and is sufficient to mediate nuclear shuttling.

Propagated annotation [?]

Comments [?]

Function Involved in the export of mRNA from the nucleus to the cytoplasm.
Subcellular location Nucleus. Cytoplasm. Note=Localizes at both the nuclear and cytoplasmic site of the pores. Shuttles between the nucleus and the cytoplasm.

Gene Ontology [?]

GO:0006397; Biological process: mRNA processing.
GO:0006406; Biological process: mRNA export from nucleus.
GO:0005634; Cellular component: nucleus.
GO:0006810; Biological process: transport.

Keywords [?]

Features [?]

From: PS51281
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       TAP-C #        

Additional information [?]

Size range 50-60 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P84149 (MEX67_CANAL)


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]