ProRule PRU00611

General rule information [?]

Accession PRU00611
Dates 19-JAN-2007 (Created)
21-NOV-2019 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51281; TAP_C
Name TAP C-terminal (TAP-C) domain
Function Members of the NXF family of shuttling transport receptors for nuclear export of mRNA have a modular structure. Their most C-terminal TAP-C domain is important for binding to FG repeat-containing nuclear pore proteins (FG-nucleoporins) and is sufficient to mediate nuclear shuttling.
Scope(s) Eukaryota
Example(s) P84149 (MEX67_CANAL);

Propagated annotation [?]

Comments [?]

FUNCTIONInvolved in the export of mRNA from the nucleus to the cytoplasm.
SUBCELLULAR LOCATIONNucleus. Cytoplasm. Note=Localizes at both the nuclear and cytoplasmic site of the pores. Shuttles between the nucleus and the cytoplasm.

Keywords [?]

Gene Ontology [?]

GO:0006397; Biological process:mRNA processing
GO:0006406; Biological process:mRNA export from nucleus
GO:0005634; Cellular component:nucleus
GO:0006810; Biological process:transport

Features [?]

From: PS51281
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="TAP-C #"

Additional information [?]

Size range 50-60 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]