ProRule PRU00611
General rule information
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| Accession | PRU00611 |
| Dates | 19-JAN-2007 (Created)
21-NOV-2019 (Last updated, Version 7) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51281; TAP_C |
Name | TAP C-terminal (TAP-C) domain |
| Function | Members of the NXF family of shuttling transport receptors for nuclear export of mRNA have a modular structure. Their most C-terminal TAP-C domain is important for binding to FG repeat-containing nuclear pore proteins (FG-nucleoporins) and is sufficient to mediate nuclear shuttling. |
| Scope(s) |
Eukaryota |
| Example(s) | P84149 (MEX67_CANAL); |
Propagated annotation
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Comments
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| FUNCTION | Involved in the export of mRNA from the nucleus to the cytoplasm. |
| SUBCELLULAR LOCATION | Nucleus. Cytoplasm. Note=Localizes at both the nuclear and cytoplasmic site of the pores. Shuttles between the nucleus and the cytoplasm. |
Keywords
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Gene Ontology
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| GO:0006397; Biological process:mRNA processing |
| GO:0006406; Biological process:mRNA export from nucleus |
| GO:0005634; Cellular component:nucleus |
| GO:0006810; Biological process:transport |
Features
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| From: PS51281 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="TAP-C #" | |||||||||
Additional information
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| Size range | 50-60 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [13] All [ 13 ]
- Retrieve set of proteins with 3D structure for this domain