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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00616


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00616
General rule information [?]

Accession PRU00616
Dates 15-JAN-2007 (Created)
21-NOV-2019 (Last updated, Version 5)
Data class Domain;
Predictors PROSITE; PS50532; HTH_IS408
Name IS408/IS1162 transposase-type HTH domain
Function The IS408 transposase-type HTH domain is a putative DNA-binding, helix-turn-helix (HTH) domain of about 80-85 amino acids, present in transposases of IS408/IS1162-like prokaryotic insertion sequences.
Scope(s) Bacteria
Example(s) Q51761;

Propagated annotation [?]

Keywords [?]


Gene Ontology [?]

GO:0003677; Molecular function:DNA binding

Features [?]

From: PS50532
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="HTH IS408-type #"
DNA_BIND 13 34 /note="H-T-H motif"

Additional information [?]

Size range 70-90 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]