PROSITE logo
Black ribbon
We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00624


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00624
General rule information [?]

Accession PRU00624
Dates 23-FEB-2007 (Created)
21-NOV-2019 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51293; SANT
Name SANT domain
Function The SANT domain is a protein-protein interaction module, which can bind to histone-tails. Although SANT domains show remarkable sequence and structural similarity to the DNA-binding helix-turn-helix (HTH) domain of the myb-like tandem repeat (see ), their function is not DNA binding.
Scope(s) Eukaryota
Example(s) Q99543; Q08773;

Propagated annotation [?]

Comments [?]

SUBCELLULAR LOCATIONNucleus.

Keywords [?]

Nucleus

Gene Ontology [?]

GO:0005515; Molecular function:protein binding
GO:0005634; Cellular component:nucleus

Features [?]

From: PS51293
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="SANT #"

Additional information [?]

Size range 30-80 amino acids
Related rules PRU00133
PRU00625
Fusion None
Repeats 1-2
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]