ProRule PRU00625
General rule information
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| Accession | PRU00625 |
| Dates | 23-FEB-2007 (Created)
27-JUN-2022 (Last updated, Version 10) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51294; HTH_MYB |
Name | Myb-type HTH DNA-binding domain |
| Function | The myb-type HTH domain is a DNA-binding, helix-turn-helix (HTH) domain of ~55 amino acids, typically occurring in a tandem repeat in eukaryotic transcription factors. Some single myb-like domains can be involved in other functions, such as protein-binding, but several single myb-like domains bind DNA (see |
| Scope(s) |
Eukaryota Viruses Alpharetrovirus |
| Example(s) | P54274 (TERF1_HUMAN); O49397 (ARR10_ARATH); |
Propagated annotation
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Comments
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| SUBCELLULAR LOCATION | Nucleus. |
Keywords
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Gene Ontology
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| GO:0003677; Molecular function:DNA binding |
| GO:0006355; Biological process:regulation of DNA-templated transcription |
| GO:0006351; Biological process:DNA-templated transcription |
| GO:0005634; Cellular component:nucleus |
Features
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| From: PS51294 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <Feature:PS51294:44-52=R-x-N-V-A-S-H-L-Q> | ||||||||||||
| DNA_BIND | entry | exit | /note="Myb-like GARP #" | |||||||||
| else | ||||||||||||
| DOMAIN | entry | exit | /note="HTH myb-type #" | |||||||||
| DNA_BIND | 30 | 55 | /note="H-T-H motif" | |||||||||
| end case | ||||||||||||
Additional information
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| Size range | 40-80 amino acids |
| Related rules |
PRU00133 PRU00624 |
| Fusion | None |
| Repeats | 1-5 |
| Topology | Undefined |
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UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [1] Eukaryota [353] Viruses [1] All [ 355 ]
- Retrieve set of proteins with 3D structure for this domain