General rule information
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Accession |
PRU00625 |
Dates |
23-FEB-2007 (Created) 21-NOV-2019 (Last updated, Version 9) |
Predictors |
PROSITE; PS51294; HTH_MYB
|
Names |
Myb-type HTH DNA-binding domain; Myb/SANT repeat |
Function |
The myb-type HTH domain is a DNA-binding, helix-turn-helix (HTH) domain of ~55 amino acids, typically occurring in a tandem repeat in eukaryotic transcription factors. Some single myb-like domains can be involved in other functions, such as protein-binding, but several single myb-like domains bind DNA (see ). |
Propagated annotation
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Subcellular location |
Nucleus. |
GO:0003677; Molecular function: DNA binding.
GO:0006355; Biological process: regulation of transcription, DNA-templated.
GO:0006351; Biological process: transcription, DNA-templated.
GO:0005634; Cellular component: nucleus.
case <Feature:PS51294:44-52=R-x-N-V-A-S-H-L-Q>
From: PS51294 |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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DNA_BIND
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entry
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exit
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Myb-like GARP #
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else
DOMAIN
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entry
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exit
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HTH myb-type #
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DNA_BIND
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30
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55
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H-T-H motif
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end case
Additional information
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Size range |
40-80 amino acids |
Related rules |
PRU00133; PRU00624 |
Repeats |
1-5 |
Topology |
Undefined |
Examples |
P54274 (TERF1_HUMAN); O49397 (ARR10_ARATH): [Recover all] |
Scope |
Eukaryota
Viruses; Alpharetrovirus |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
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