ProRule PRU00627
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU00627 |
| Accession | PRU00627 |
| Dates | 10-JUL-2007 (Created)
21-NOV-2019 (Last updated, Version 4) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51025; PWI |
Name | PWI domain |
| Function | The PWI domain, named after a highly conserved PWI tri-peptide located within its N-terminal region, is a ~80 amino acid RNA/DNA-binding domain that has an equal preference for single- and double-stranded nucleic acids and is likely to have multiple important functions in pre-mRNA processing. |
| Scope(s) |
Eukaryota |
| Example(s) | Q5ZMJ9 (SRRM1_CHICK); |
Propagated annotation
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Comments
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| SUBCELLULAR LOCATION | Nucleus. |
Keywords
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Gene Ontology
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| GO:0005634; Cellular component:nucleus |
| GO:0006397; Biological process:mRNA processing |
Features
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| From: PS51025 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="PWI #" | |||||||||
Additional information
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| Size range | 85-105 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Not cytoplasmic |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [15] All [ 15 ]
- Retrieve set of proteins with 3D structure for this domain