PROSITE logo
Black ribbon
We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00627


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00627
General rule information [?]

Accession PRU00627
Dates 10-JUL-2007 (Created)
21-NOV-2019 (Last updated, Version 5)
Data class Domain;
Predictors PROSITE; PS51025; PWI
Name PWI domain
Function The PWI domain, named after a highly conserved PWI tri-peptide located within its N-terminal region, is a ~80 amino acid RNA/DNA-binding domain that has an equal preference for single- and double-stranded nucleic acids and is likely to have multiple important functions in pre-mRNA processing.
Scope(s) Eukaryota
Example(s) Q5ZMJ9;

Propagated annotation [?]

Comments [?]

SUBCELLULAR LOCATIONNucleus.

Keywords [?]

Nucleus
mRNA processing

Gene Ontology [?]

GO:0005634; Cellular component:nucleus
GO:0006397; Biological process:mRNA processing

Features [?]

From: PS51025
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="PWI #"

Additional information [?]

Size range 85-105 amino acids
Related rules None
Fusion None
Repeats 1
Topology Not cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]