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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00651


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00651
General rule information [?]

Accession PRU00651
Dates 22-DEC-2008 (Created)
21-NOV-2019 (Last updated, Version 6)
Data class Domain;
Predictors PROSITE; PS51321; TFIIS_CENTRAL
Name TFIIS central domain
Function The transcription factor IIS (TFIIS) is a modular factor that comprises an N-terminal domain, a central domain, and a C-terminal TFIIS-type zinc finger. The central domain is conserved in TFIIS homologues and interacts with RNA polymerase II.
Scope(s) Eukaryota
Viruses
Example(s) P07273;

Propagated annotation [?]

Comments [?]

case <OC:Eukaryota>
SUBCELLULAR LOCATIONNucleus.
end case

Keywords [?]

Nucleus
end case

Gene Ontology [?]

case <OCellular component:Eukaryota>
GO:0005634; Cellular component:nucleus

Features [?]

From: PS51321
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="TFIIS central #"

Additional information [?]

Size range 75-140 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]