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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00667


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00667
General rule information [?]

Accession PRU00667
Dates 02-MAY-2016 (Created)
21-NOV-2019 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS51337; B12_BINDING_NTER
Name B12-binding N-terminal domain
Function In methionine synthase the cobalamin cofactor is sandwiched between the B12-binding domain and an ~90 residues N-terminal domain forming a helical bundle comprising two pairs of antiparallel helices.
Scope(s) Archaea
Methanosarcina
Bacteria
Eukaryota
Example(s) Q55786;

Propagated annotation [?]

Features [?]

From: PS51337
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="B12-binding N-terminal"

Additional information [?]

Size range 34-112 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]