We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00691
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00691
General rule information
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| Accession | PRU00691 |
| Dates | 05-MAR-2010 (Created)
08-OCT-2024 (Last updated, Version 10) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51352; THIOREDOXIN_2 |
Name | thioredoxin domain |
| Function | The thioredoxin domain participate in various redox reactions via the reversible oxidation of an active center disulfide bond. |
| Scope(s) |
Eukaryota Bacteria Viruses Archaea Methanobacteriati |
| Example(s) | P0AEG4; |
Propagated annotation
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Keywords
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| case <FTTag:disulf> | |
| Disulfide bond | |
| end case | |
Gene Ontology
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| GO:0045454; Biological process:cell redox homeostasis |
Features
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| From: PS51352 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Thioredoxin #" | |||||||||
| DISULFID | 42 | 45 | /note="Redox-active" | disulf | C-x*-C | |||||||
Additional information
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| Size range | 100-200 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-4 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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