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ProRule PRU00692


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PURL: https://purl.expasy.org/prosite/rule/PRU00692
General rule information [?]

Accession PRU00692
Dates 31-JAN-2008 (Created)
19-NOV-2022 (Last updated, Version 8)
Data class Domain;
Predictors PROSITE; PS51359; COX5B_2
Name Cytochrome c oxidase subunit Vb, zinc binding domain
Function This domain occurs in a subunit which forms a part of the cytochrome c oxidase (EC 1.9.3.1) enzymatic complex. It contains 3 to 4 conserved cysteine residues which bind a zinc atom.
Scope(s) Eukaryota
Example(s) Q5S3G4 (COX5B_PIG);

Propagated annotation [?]

Identifier, protein and gene names [?]

case <Feature:PS51359:61=C> and <Feature:PS51359:84=C> and <Feature:PS51359:87=C>
Protein name + AltName: Full=cytochrome c oxidase subunit;

Comments [?]

FUNCTIONThis protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
SUBCELLULAR LOCATIONMitochondrion inner membrane.
end case
SIMILARITYBelongs to the cytochrome c oxidase Vb family.

Keywords [?]

Mitochondrion inner membrane
Membrane
Metal-binding
Mitochondrion
Zinc
end case

Gene Ontology [?]

GO:0016020; Cellular component:membrane
GO:0046872; Molecular function:metal ion binding
GO:0005739; Cellular component:mitochondrion
GO:0008270; Molecular function:zinc ion binding

Cross-references [?]

PROSITE PS00848; COX5B_1; 1;

Features [?]

From: PS51359
Key From To Description Tag Condition FTGroup
BINDING 61 61 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C
BINDING 63 63 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C
BINDING 84 84 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C
BINDING 87 87 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C

Additional information [?]

Size range 90-110 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]