ProRule PRU00692
General rule information
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| Accession | PRU00692 |
| Dates | 31-JAN-2008 (Created)
19-NOV-2022 (Last updated, Version 7) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51359; COX5B_2 |
Name | Cytochrome c oxidase subunit Vb, zinc binding domain |
| Function | This domain occurs in a subunit which forms a part of the cytochrome c oxidase (EC 1.9.3.1) enzymatic complex. It contains 3 to 4 conserved cysteine residues which bind a zinc atom. |
| Scope(s) |
Eukaryota |
| Example(s) | Q5S3G4 (COX5B_PIG); |
Propagated annotation
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Identifier, protein and gene names
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| case <Feature:PS51359:61=C> and <Feature:PS51359:84=C> and <Feature:PS51359:87=C> | |
| Protein name | + AltName: Full=cytochrome c oxidase subunit; |
Comments
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| FUNCTION | This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. |
| SUBCELLULAR LOCATION | Mitochondrion inner membrane. |
| end case | |
| SIMILARITY | Belongs to the cytochrome c oxidase Vb family. |
Keywords
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Gene Ontology
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| GO:0016020; Cellular component:membrane |
| GO:0046872; Molecular function:metal ion binding |
| GO:0005739; Cellular component:mitochondrion |
| GO:0008270; Molecular function:zinc ion binding |
Cross-references
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| PROSITE | PS00848; COX5B_1; 1; |
Features
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| From: PS51359 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 61 | 61 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | ||||||||
| BINDING | 63 | 63 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | ||||||||
| BINDING | 84 | 84 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | ||||||||
| BINDING | 87 | 87 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | ||||||||
Additional information
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| Size range | 90-110 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [14] All [ 14 ]
- Retrieve set of proteins with 3D structure for this domain