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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00703


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00703
General rule information [?]

Accession PRU00703
Dates 22-DEC-2011 (Created)
21-NOV-2019 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS51371; CBS
Name CBS domain
Function CBS domains act as autoinhibitory regulatory units in some proteins and activate or further inhibit protein function upon binding to adenosine nucleotides (AMP, ADP, ATP, S-adenosyl methionine, NAD, diadenosine polyphosphates).
Scope(s) Eukaryota
Bacteria
Archaea
Example(s) A3LQC5;

Propagated annotation [?]

Keywords [?]


Features [?]

From: PS51371
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="CBS #"

Additional information [?]

Size range 26-97 amino acids
Related rules None
Fusion None
Repeats 1-4
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]