ProRule PRU00725

General rule information [?]

Accession PRU00725
Dates 8-APR-2009 (Created)
21-NOV-2019 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS51392; KEN
Name KEN domain
Function The dimerization of the kinase domain activates the ribonuclease function of the ~135-residue globular kinase-extension nuclease (KEN) domain made of eight helices.
Scope(s) Eukaryota
Example(s) P32361 (IRE1_YEAST);

Propagated annotation [?]

Features [?]

From: PS51392
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="KEN #"

Additional information [?]

Size range 119-189 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]