ProRule PRU00725
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU00725 |
| Accession | PRU00725 |
| Dates | 8-APR-2009 (Created)
21-NOV-2019 (Last updated, Version 4) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51392; KEN |
Name | KEN domain |
| Function | The dimerization of the kinase domain activates the ribonuclease function of the ~135-residue globular kinase-extension nuclease (KEN) domain made of eight helices. |
| Scope(s) |
Eukaryota |
| Example(s) | P32361 (IRE1_YEAST); |
Propagated annotation
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Features
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| From: PS51392 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="KEN #" | |||||||||
Additional information
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| Size range | 119-189 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [22] All [ 22 ]
- Retrieve set of proteins with 3D structure for this domain