ProRule PRU00732
General rule information
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| Accession | PRU00732 |
| Dates | 22-DEC-2008 (Created)
21-NOV-2019 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51399; SEP |
Name | SEP domain |
| Function | The function of the SEP domain is as yet unknown but it has been proposed to act as a reversible competitive inhibitor of the lysosomal cysteine protease cathepsin L. |
| Scope(s) |
Eukaryota |
| Example(s) | Q9UNZ2 (NSF1C_HUMAN); |
Propagated annotation
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Features
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| From: PS51399 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="SEP #" | |||||||||
Additional information
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| Size range | 60-70 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-2 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [25] All [ 25 ]
- Retrieve set of proteins with 3D structure for this domain