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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00732


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00732
General rule information [?]

Accession PRU00732
Dates 22-DEC-2008 (Created)
21-NOV-2019 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS51399; SEP
Name SEP domain
Function The function of the SEP domain is as yet unknown but it has been proposed to act as a reversible competitive inhibitor of the lysosomal cysteine protease cathepsin L.
Scope(s) Eukaryota
Example(s) Q9UNZ2;

Propagated annotation [?]

Features [?]

From: PS51399
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="SEP #"

Additional information [?]

Size range 60-70 amino acids
Related rules None
Fusion None
Repeats 1-2
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]