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ProRule PRU00734


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PURL: https://purl.expasy.org/prosite/rule/PRU00734
General rule information [?]

Accession PRU00734
Dates 19-DEC-2008 (Created)
19-NOV-2022 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51401; CHORD
Name CHORD domain
Function Cysteine- and histidine-rich domains (CHORDs) are 60-amino acid modules that bind two zinc ions.
Scope(s) Eukaryota
Example(s) Q9UHD1 (CHRD1_HUMAN);

Propagated annotation [?]

Keywords [?]

case <FTGroup:1> or <FTGroup:2>
Zinc
Metal-binding
end case

Features [?]

From: PS51401
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="CHORD #"
BINDING 1 1 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 C 1
BINDING 6 6 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 C 1
BINDING 20 20 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 C 1
BINDING 23 23 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 H 2
BINDING 38 38 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 C 2
BINDING 39 39 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 C 2
BINDING 55 55 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 C 2
BINDING 60 60 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 H 1

Additional information [?]

Size range 55-65 amino acids
Related rules None
Fusion None
Repeats 1-2
Topology Not cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]