ProRule PRU00734
General rule information
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Accession | PRU00734 |
Dates | 19-DEC-2008 (Created)
19-NOV-2022 (Last updated, Version 6) |
Data class | Domain; |
Predictors |
PROSITE; PS51401; CHORD |
Name | CHORD domain |
Function | Cysteine- and histidine-rich domains (CHORDs) are 60-amino acid modules that bind two zinc ions. |
Scope(s) |
Eukaryota |
Example(s) | Q9UHD1 (CHRD1_HUMAN); |
Propagated annotation
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Keywords
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case <FTGroup:1> or <FTGroup:2> | |
Zinc | |
Metal-binding | |
end case |
Features
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From: PS51401 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | /note="CHORD #" | |||||||||
BINDING | 1 | 1 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
C | 1 | |||||||
BINDING | 6 | 6 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
C | 1 | |||||||
BINDING | 20 | 20 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
C | 1 | |||||||
BINDING | 23 | 23 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2" |
H | 2 | |||||||
BINDING | 38 | 38 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2" |
C | 2 | |||||||
BINDING | 39 | 39 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2" |
C | 2 | |||||||
BINDING | 55 | 55 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2" |
C | 2 | |||||||
BINDING | 60 | 60 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" |
H | 1 |
Additional information
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Size range | 55-65 amino acids |
Related rules |
None |
Fusion | None |
Repeats | 1-2 |
Topology | Not cytoplasmic |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [17] All [ 17 ]
- Retrieve set of proteins with 3D structure for this domain