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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00753


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00753
General rule information [?]

Accession PRU00753
Dates 03-FEB-2025 (Created)
11-FEB-2025 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51419; RAB
Name Small GTPase Rab-type domain
Function GTP-binding proteins involved in vesicular traffic.
Scope(s) Eukaryota
Example(s) P62820;

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the small GTPase superfamily. Rab family.

Keywords [?]

GTP-binding
Nucleotide-binding

Gene Ontology [?]

GO:0005525; Molecular function:GTP binding
GO:0003924; Molecular function:GTPase activity

Features [?]

From: PS51419
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Small GTPase Rab-type #"
REGION 32 40 /note="Switch-I #"
REGION 63 79 /note="Switch-II #"

Additional information [?]

Size range 183-331 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]